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2008年以前の業績

 

 

Phonon Dispersion and Heat Capacity in Microbial Poly (e-L-lysine)(M-e-PL)
Mahendra Singh, Abhishek K. Mishra, Navnit K. Misra, Poonam Tandon, Ko-Ki Kunimoto and V. D. Gupta
Polymer Journal, 40(6), 503-512 (2008)

 

 

Effect of Cyclodextrins on the Thermal Epimerization of Tea Catechins
Hisako Okumura, Masaki Ichitani, Takanobu Takihara, and Ko-Ki Kunimoto
Food Science and Technology Research, 14(1), 83-88 (2008)

 

 

Facile Quantitative Analysis of Gallated Catechins in Tea Bevaratge by UV Absorption Spectra
Hisako Okumura, Masaki Ichitani, Takanobu Takihara, and Ko-Ki Kunimoto
Japan J. Food Chem.(日本食品化学学会誌), 14(3), 128-133 (2007)

 

 

Crystal structure of 4,4'-diphenyl-2,2'-dithioxo-[4,4'-biimidazolidine]-5,5'-dione bis(dimethylsulfoxide) solvate
Toshikazu Ogawa, Soh-ichi Kitho, Masaki Ichitani, Akio Kuwae, Kazuhiko Hanai and Ko-Ki Kunimoto
Anal. Sci., X-ray Structure Analysis Online, 32, X201-X202, (2007)

 

 

Crystal Structure of 5-Phenyl-2-thioxo-4-imidazolidinone
Toshikazu Ogawa, Soh-ichi Kitho, Masaki Ichitani, Akio Kuwae, Kazuhiko Hanai and Ko-Ki Kunimoto
Anal. Sci., X-ray Structure Analysis Online, 32, X199-X200, (2007)

 

 

Synthesis, Absorption and Fluorescence Properties and Crystal Structures of 7-Aminocoumarin Derivatives
Noriko Kitamura, Tomoyoshi Fukagawa, Shigeru Kohtani, Soh-Ichi Kitoh, Ko-Ki Kunimoto and Ryoichi Nakagaki
J. Photochem. Photobiol. A: Chemistry, 188(2-3), 378-386 (2007)

 

 

Vibrational and NMR spectra and structures of lithium pyruvate monohydrate
K. Hanai, A. Kuwae, Y. Sugawa, K. Kunimoto, and Shiro Maeda
J. Mol. Struct., 837, 101-106 (2007)

 

 

Aggregation behavior of dabsylated poly(e-L-lysine) in aqueous DMSO solution
C. Sasaki, T. Hamada, H. Okumura, S. Maeda, J. Muranaka, A. Kuwae, K. Hanai, and K. Kunimoto
Polymer Bulletin, 57(5), 747-756 (2006)

 

 

Crystal Structure of an Angular Carbazole-Coumarin Hybrid Dye
T. Fukagawa, N. Kitamura, S. Kohtani, S.Kitoh, K. Kunimoto and R. Nakagaki
Anal. Sci., X-ray Structure Analysis Online, 22(9), X219-X220 (2006)

 

 

Crystal Structure of a Pyrrolyl-Substituted 4-Methylcoumarin
T. Fukagawa, N. Kitamura, S. Kohtani, S.Kitoh, K. Kunimoto and R. Nakagaki
Anal. Sci., X-ray Structure Analysis Online, 22(7), x187-x188 (2006)

 

 

Crystal Structure of a Linear Carbazole-Coumarin Hybrid Dye
T. Fukagawa, N. Kitamura, S. Kohtani, S.Kitoh, K. Kunimoto and R. Nakagaki
Anal. Sci., X-ray Structure Analysis Online, 22(7), x191-x192 (2006)

 

 

Crystal Structure of a Pyrrolyl-Substituted 4-Trifluoromethylcoumarin
T. Fukagawa, N. Kitamura, S. Kohtani, S.Kitoh, K. Kunimoto and R. Nakagaki
Anal. Sci., X-ray Structure Analysis Online, 22(7), X189-x190 (2006)

 

 

(R)-1-Phenylethylammonium N-tetradecanoyl-L-phenylalaninate monohydrate
T. Ogawa, A. Ohta, S. Miyagishi, and K. Kunimoto
Acta Cryst. E62, o153-o155 (2006)

 

 

Aggregation behavior of dabsylated amino acids in aqueous solution
H. Hayashi, C. Sasaki, K. Kunimoto, S. Maeda, S. Hosoi, A. Kuwae and K. Hanai
BUNSEKI KAGAKU, 54(9), 799-805 (2005)

 

 

Structural investigation of microbial poly(e-L-lysine) derivatives with azo dyes by solid-state 13C and 15N NMR
S. Maeda , T. Mori, C. Sasaki, K. Kunimoto, A. Kuwae, and K. Hanai
Polymer Bulletin, 53, 259-267 (2005)

 

 

Conglomerate Formation and Crystal Structure of 4-Phenyl-1,3-thiazolidin-2-one
S. Kitoh, A. Kubota, K. Kunimoto, A. Kuwae and K. Hanai
J. Mol. Struct., 737, 277-282 (2005)

 

 

Crystal Structure of 4-Dimethylaminoazobenzene-4'-sulfonyl-L-tryptophan Dimethylsulfoxide Solvate
C. Sasaki, S. Kitoh, H. Hayashi and K. Kunimoto
Anal. Sci., 20, x117-x118 (2004)  pdf

 

 

Crystal structure and Spectroscopic Characterization of Chiral and Racemic 4-Phenyl-1,3-oxazolidin-2-one.
S. Kitoh, H. Senda, K. Kunimoto, S. Maeda, A. Kuwae and K. Hanai,
Cryst. Res. Technol., 39(4), 375-381 (2004)  pdf

 

 

放線菌由来ポリ-ε-リジンの分子構造 
前田  史郎,森  貴志,国本浩喜,佐々木千鶴 
高分子加工, 11月号, 516-522 (2003).   pdf

 

 

Crystal Structure of chiral and racemic 4-Methyl-5-phenyl-1,3-oxazolidine-2-thione. 
S. Kitoh, H. Senda and K. Kunimoto, 
Anal. Sci., 19, x15-x16 (2003).   pdf

 

 

Characterization of Microbial Poly (e-L-lysine) by FT-IR, Raman and Solid State 13C NMR spectroscopies. 
S. Maeda, K. Kunimoto, C. Sasaki, A. Kuwae and K. Hanai, 
J. Mol. Struct., 655(1), 149-155 (2003).   pdf

 

 

Crystal Structure of 2-Trifluoromethyl-4'-dimethylaminoazobenzene. 
C. Sasaki, S. Kitoh, K. Yamada, K. Kunimoto, S. Maeda, A. Kuwae and K. Hanai, 
Anal. Sci., 19, X1-X3 (2003).   pdf

 

 

Crystal Structure of 4-N,N-(dimethylamino)-2,3,5,6-tetrafluorobenzonitrile. 
R. Nakagaki, S. Kohtani, Y. Nakamura, M. Okamura, S. Kitoh and K. Kunimoto, 
Anal. Sci., 19, X5-X6 (2003).   pdf

 

 

Uniformly Sized Molecularly Imprinted Polymer for (S)-Nilvadipine.  Comparison of Chral Recognition Ability with HPLC Chiral Stationary Phases Based on a Protein. 
Q. Fu, H. Sanbe, C. Kagawa, K. Kunimoto and J. Haginaka , 
Anal. Chem., 75, 191-198 (2003).   pdf

 

 

Crystal Structures and Vibrational Spectra  of Racemic and Chiral  4-Phenyl-1,3-Oxazolidine-2-thione. 
S. Kitoh, K. Kunimoto, N. Funaki, H. Senda, A. Kuwae, K. Hanai, 
J. Chem. Crystallogr., 32(12), 533-539 (2002).   pdf

 

 

Crystal and Molecular Structure of Racemic and Chiral 4-Phenyl-1,3-thiazolidine-2-thione. 
K. Kunimoto, S. Kitoh, M. Ichitani, N. Funaki, A. Kuwae, K. Hanai , 
Heterocycles, 57(11), 2011-2019 (2002).   pdf

 

 

Crystal Structure of 2-Benzoyl-3,4,5,6-tetrachlorobenzoic  Acid. 
S. Kitoh, T. Matsushima, T. Matsumoto, H. Senda, K. Kunimoto, 
Anal. Sci., 18, 615-616 (2002)   pdf

 

 

Rig-Chain Tautomerism of Halogenated Phenolphthaleins : Vibrational Spectroscopic and Semiempirical MO Study. 
K. Kunimoto, H. Sugiura, T. Kato, H. Senda, A. Kuwae and K. Hanai, 
Heterocycles, 57(5), 895-901 (2002)   pdf

 

 

Crystal Structure of o-(p-N,N-Dimethylaminobenzoyl)benzoic Acid, 
S. Kitoh, T. Matsushima, N. Matsumoto, H. Senda, K. Kunimoto, A. Kuwae, A. Noguchi and K. Hanai 
Anal. Sci., 18, 371-372 (2002).   pdf

 

 

A Comparative Vibarational and NMR study of cis-Cinnamic Acid Polymorphs and trans-Cinnamon Acid. 
K. Hanai, A.Kuwae, T. Takai, H. Senda, and K. Kunimoto 
Spectrochim Acta, PartA , 57, 513-519 (2001)   pdf

 

 

Molecular Structure and Vibrational Spectra of Phenolphthalein and its Dianion, 
K. Kunimoto, H. Sugiura, T. Kato, A. Kuwae and K. Hanai, 
Spectrochim. Acta, Part A,  57, 265-271(2001)   pdf

 

 

Cystal Structure of Tetramethylformamidium disulfide m-oxo-bis[trichloroferrate(III)]. 
H. Senda, S. Kitoh, T. Suganami and K. Kunimoto, 
Anal Sci., 16, 1003-1004 (2001)   pdf

 

 

Polymorphism of 4-Fluorophenylpyruvic Acid Studied By X-ray Crystallography and Vibrational Spectroscopy. 
K. Kunimoto, K. Kimura, T. Takai, H. Senda, A. Kuwae and K. Hanai, 
Spectrosc. Lett., 33(4), (2000)   pdf

 

 

Diastereomeric resolution of trans-1,2-cyclohexanedicarboxylic acid with (R)-1-phenyl-ethylamine. 
K. Kimura, T. Suda, Y. Watanabe, H. Senda and K. Kunimoto, 
ACGC Chem Res,. Commun., 9, 25-30 (1999).   pdf

 

 

Crystal structure of (1R,2R)-trans-1,2-cyclohexanedicarboxylic acid-(R)-phenylethylamine salt. 
K. Kimura, Y. Watanabe, T. Suda, H. Senda, S. Hosoi, T. Ohta and K. Kunimoto, 
Anal.  Sci., 15, 609-610 (1999).   pdf

 

 

Crystal structure of phenolphthalein. 
H. Sugiura, T. Kato, H. Senda, K. Kunimoto, A. Kuwae and K. Hanai, 
Anal. Sci., 15, 611-612 (1999).   pdf

 

 

Polymorphism of phenylpyruvic acid studied by IR, Raman and solid state 13C NMR spectroscopy. 
H. Lee, K. Kimura, T. Takai, H. Senda, A. Kuwae and K. Hanai, 
Spectroschim Acta, Part A, 55, 2877-2882 (1999).   pdf

 

 

Keto-enol tautomerism of mono-substituted phenylpyruvic acids as studied by NMR and PM3 calculations. 
T. Takai, H. Senda, H. Lee, A. Kuwae and K. Hanai, 
Spectrosc. Lett., 31, 379-395 (1998).   pdf

 

 

Molecular structure of methyl phenylpyruvates studied by 1H NMR and IR spectroscopies and quantum mechanical calculations. 
H. Lee, T. Takai, H. Senda, A. Kuwae and K. Hanai, 
J. Mol Struct., 449, 69-75 (1998)   pdf

 

 

Molecular structure and dimerization of D-cycloserine in the solid state. 
H. Lee, N. Takeuchi, H. Senda, A. Kuwae and K. Hanai, 
Spectrosc. Lett., 31, 1217-1222 (1998).   pdf

 

 

IR study on aqueous solution behavior of D-cycloserine. 
H. Lee, H. Yamaguchi, H. Senda, A. Kuwae and K. Hanai, 
Spectrosc. Lett., 30, 685-700 (1997).   pdf

 

 

X-ray and vibrational studies of methyl (N-benzoyl-aminooxy) acetate. 
H. Lee, H. Yamaguchi, H. Senda, A. Kuwae, and K. Hanai, 
Spectrochim. Acta, Part A, 52, 297-303 (1996).   pdf

 

 

Synthesis and conformation of monodispersed oligo(e-L-lysine)mers studied by CD and IR spectroscopies. 
H. Lee, H. Yamaguchi, D. Fujimori, T. Ohnishi, A. Nishida, and H. Yamamoto, 
Spectrosc. Lett., 28, 177-190 (1995).   pdf

 

 

Crystal and molecular structures of a low-melting polymorph of allocinnamic acid. 
H.-H. Lee, H. Senda, K. Oyama, A. Kuwae, and K. Hanai, 
Bull. Chem. Soc. Jpn., 67, 2574-2576 (1994).   pdf

 

 

Structure of 3-phenyl-2-thiopyruvic acid as studied by FT-IR, FT-Raman ans NMR spectroscopies. 
H.-H. Lee, A. Kuwae, and K. Hanai, 
Spectrosc. Lett., 27, 787-799 (1994).   pdf

 

 

Crystal and molecular structures of allocinnamic acid. 
H.-H. Lee, H. Senda, A. Kuwae, and K. Hanai, 
Bull. Chem. Soc. Jpn., 67, 1475-1478 (1994).   pdf

 

 

PEG-papain catalyzed synthesis of a Kyotorphin derivative in aqueous organic media. 
H.-H. Lee, H. Fukushi, K. Oyama, and K. Aso, 
Biotechnol. Lett., 15, 833-836 (1993).   pdf

 

 

HPLC fractionation of oligo(e-L-lysine)mers and their 1H NMR characteristics.
H. Fukushi, K. Oyama, M. Hatakeyama, D. Fujimori, and H. Lee,
Chem. Express, 8, 745-748 (1993).  pdf

 

 

Solid state structure of phenylpyruvates as studied by high resolution 13C NMR spectroscopy. 
A. Kuwae, K. Hanai, K. Oyama, M. Uchino, and H. Lee, 
Spectrochim. Acta, 49, 125-133 (1993).   pdf

 

 

Lipase catalyzed optical resolution of acrtylenic alcohols. 
A. Fujiwara, H. Fukushi, and H. Lee, 
Chem. Express, 7, 765-768 (1992).   pdf

 

 

Trypsin-catalyzed synthesis of the arginyl-arginine dipeptide from L-arginine ethyl ester. 
K. Aso, H. Kodaka, H. Fukushi, and H. Lee, 
Biotech. Lett., 14, 451-454 (1992).   pdf

 

 

Characterization of a novel monothioxo cyclodipeptide by IR, 1H and 13C NMR spectroscopies. 
M. Uchino and H. Lee, 
Chem. Express, 6, 833-836 (1991)   pdf

 

 

Microbial production and conformation of poly(e-L-lysine).
H. Lee, K. Oyama, J. Hiraki, M. Hatakeyama, Y. Kurokawa, and H. Morita,
Chem. Express, 6, 683-686 (1991).  pdf

 

 

Conformational study of methyl methoxyacetate and its sulfur substituted isologs by IR and Raman spectroscopies. 
M. Uchino and H. Lee, 
Chem. Express, 6, 571-574 (1991)   pdf

 

 

Papain catalyzed polymerization of L-a-amino acid methyl esters with hydrophobic side chains. 
H. Lee, H. Fukushi, M. Uchino, and Y. Fukazawa, 
Chem. Express, 5, 741-744 (1990).   pdf

 

 

Chromophoric acyl-enzyme intermediates formed by the polyethylene glycol-modified papain in benzene. 
H. Lee, 
Chem. Express, 5, 469-472 (1990).   pdf

 

 

Polyethylene glycol-modified papain catalyzed oligopeptide synthesis from esters of L-aspartic acids and L-glutamic acids in benzene. 
T. Uemura, M. Fujimori, H. Lee, S. Ikeda, and K. Aso, 
Agric. Biol. Chem., 54,  2277-2281 (1990).   pdf

 

 

Sturcture of enzyme-bound substrates : Resonance Raman and kinetic evidence for differential enzyme-substrate contacts in N-(pentafluorobenzoyl)glycine dithioacyl and thioacyl papain. 
H. Lee, R. H. Angus, A. C. Storer, and P. R. Carey, 
J. Mol. Struct., 214, 1-13 (1989).   pdf

 

 

Enzymatic synthesis of chiral sec-alcohols and their NMR chemical shifts induced by a lanthanide shift reagent. 
N. Yoshida, H. Morita, K. Oyama,  and H. Lee, 
Chem. Express, 4, 721-724 (1989).   pdf

 

 

Substrate specificity of polyethylene glycol-modified papain catalyzed peptide bond synthesis in benzene. 
H. Lee, H. Fukushi, M. Uchino, K. Sato, K. Takahashi, Y. Inada, and K. Aso, 
Chem. Express, 4, 253-256 (1989).   pdf

 

 

Striking changes observed in key acyl-enzyme linkages by resonance Raman experiments near 77 K. 
 P. J. Tonge, H. Lee, L. S. Sans Cartier, B. P. Ruzsicska, and P. R. Carey, 
 J. Am. Chem. Soc., 111, 1496-1497 (1989).   pdf

 

 

Polyethylene glycol-modified papain catalyzes peptide bond formationハin benzene. 
H. Lee, K. Takahashi, Y. Kodera, K. Ohwada, T. Tsuzuki, A. Matsushima, and Y. Inada, 
Biotech. Lett., 5(6), 403-407(1988).   pdf

 

 

Conformational variability in enzyme's active site : resonance Raman evidence for different acyl group conformations in N-acylglycine and N-acylalanine dithioacylpapains. 
R. H. Angus, H. Lee, A. C. Storer, and P. R. Carey, 
Biochemistry, 27, 258-263 (1988).   pdf

 

 

Conformational states of N-acylalanine dithioesters : Correlation of resonance Raman spectra with structures. 
H. Lee, R. H. Angus, A. C. Storer, K. I. Varughese, and P. R. Carey, 
Biochemistry, 27, 250-257 (1988).   pdf

 

 

Resonance Raman spectroscopic evidence for the formation of covalent complexes between N-acylamino acid dithioesters and mercury papain. 
H. Lee, R. H. Angus, P. R. Carey, and A. C. Storer 
Can. J. Chem., 65, 1521-1526 (1987).   pdf

 

 

Tautomeric equilibrium of salicylidene Schiff base. uv-visible absorption and Raman spectroscopic studies. 
H. Lee and T. Kitagawa, 
Bull. Chem. Soc. Jpn., 59, 2897-2898(1986).   pdf

 

 

Tautomeric equilibrium of salicylidene Schiff base. uv-visible absorption and Raman spectroscopic studies. 
H. Lee and T. Kitagawa, 
Bull. Chem. Soc. Jpn., 59, 2897-2898 (1986).   pdf

 

 

The structure and resonance Raman spectra-structure correlations for methoxycarbonyl-L-phenylalanyl-L-alanine ethyl dithioester. 
K. I. Varughese, R. H. Angus, P. R. Carey, H. Lee, and A. C. Storer, 
Can. J. Chem., 64, 1668-1673 (1986).   pdf

 

 

Conformational activation of acylpapains and acylcathepsin B's : resonance Raman and kinetic evidence. 
R. H. Angus, P. R. Carey, H. Lee, and A. C. Storer, 
Biochemistry, 25, 3304-3310 (1986).   pdf

 

 

Measurement of the intensity of resonance Raman bands of aromatic compounds in the solid state by the divided-disk method. 
I. Tsukamoto, H. Lee, H. Uchida, and K. Machida, 
J. Raman Spectrosc., 16(4), 280-283 (1985).   pdf

 

 

The structure and resonance Raman spectra-structure correlations for N-benzoyl-DL-alanine ethyl dithioester. 
R. H. Angus, P. R. Carey, H. Lee, A. C. Storer and K. I. Varughese, 
Can. J. Chem., 63(8), 2169-2175 (1985).   pdf

 

 

Vibrational spectra and rotational isomerism of simple dialkyl dithioesters and N-acylglycine ethyl dithioesters, thiolesters and dioxygenesters. 
P. R. Carey, H. Lee, Y. Ozaki and A. C. Storer, 
J. Mol. Struct., 126, 261-270 (1985).   pdf

 

 

Identity of acyl group conformations in the active sites of papain and cathepsin B by resonance Raman spectroscopy. 
P. R. Carey, R. H. Angus, H. Lee, and A. C. Storer, 
J. Biol. Chem., 259(23), 14357-14360 (1984).   pdf

 

 

Conformational studies of N-acyl amino acid esters and thiol esters by FT-IR and X-ray crystallography : Evidence for a N...S interaction in thiol esters. 
C. P. Huber, P.R. Carey, S.-C. Hsi, H. Lee and A. C. Storer, 
J. Am. Chem. Soc., 106, 8263-8268 (1984).   pdf

 

 

Rate-structure correlation for enzyme-substrate intermediates : Resonance Raman and kinetic studies on some N-benzoylglycine (dithioacyl)papains. 
P.R. Carey, H. Lee, Y. Ozaki and A. C. Storer, 
J. Am. Chem. Soc., 106, 8258-8262 (1984).   pdf

 

 

Comparative resonance Raman spectroscopic and kinetic studies of acyl enzymes involving papain, actinidin and papaya peptidase II. 
K. Brocklehurst, P. R. Carey, H. Lee, E. Salih, and A. C. Storer, 
Biochem. J., 223, 649-657 (1984).   pdf

 

 

N-acylglycine dithioesters form enethoilates near pH 9. 
H. Lee, P. R. Carey, and A. C. Storer, 
Can. J. Chem., 62, 763-767 (1984).   pdf

 

 

Multichannel resonance Raman experiments on carboxypeptidases A catalyzed hydrolysis under cryoenzymological conditions. 
S. J. Hoffman, S. S.-T. Chu, H. Lee, E. T. Kaiser, and P. R. Carey, 
J. Am. Chem. Soc., 105, 6971-6973 (1983).   pdf

 

 

Relaxed and perturbed substrate conformation in enzyme active sites: Evidence from multichannel resonance Raman spectra. 
A. C. Storer, H. Lee, and P. R. Carey, 
Biochemistry, 22, 4789-4796 (1983).   pdf

 

 

Conformational states of N-glycine dithioesters : resonance Raman studies of isotopically substituted models for enzyme-substrate complex. 
H. Lee, A. C. Storer, and P. R. Carey, 
Biochemistry, 22, 4781-4789 (1983).   pdf

 

 

UV excited resonance Raman spectra of methyl orange and its complex with cetyltrimethylammonium bromide. 
H. Lee, K. Machida, A. Kuwae, and I. Harada, 
J. Raman Spectrosc., 14(2), 126-129 (1983).   pdf

 

 

Direct evidence for the site of protonation of p-aminoazobenzene by 15N and 13C nuclear magnetic resonance spectroscopy. 
Y. Kuroda, H. Lee, and A. Kuwae, 
J. Phys. Chem., 84, 3417-3423 (1980).   pdf

 

 

Resonance Raman spectra and structure of p-aminoazobenzene dyes in diprotonated form. 
H. Lee, K. Machida, A. Kuwae, and Y. Saito, 
J. Mol. Struct., 68, 51-57 (1980).   pdf

 

 

Resonance Raman spectra of D and 15N isotopes of methyl orange in aqueous solutions. 
K. Machida, H. Lee, and A. Kuwae, 
J. Raman Spectrosc., 9(3), 198-201 (1980).   pdf

 

 

Resonance Raman spectra of sulfophthalein dyes in aqueous solutions. 
K. Machida, H. Lee, and T. Uno, 
J. Raman Spectrosc., 8(3), 172-176 (1979).   pdf

 

 

Resonance Raman spectra of p-hydroxyazobenzene and its ring deuterated derivatives in the strongly acidic solution. 
K. Machida, H. Lee, and T. Uno, 
J. Raman Spectrosc., 7(4), 184-187 (1978).   pdf

 

 

Resonance Raman spectra of p-hydroxyazobenzne and its ring deuterated  derivatives. 
T. Uno, H. Lee, Y. saito, and K. Machida, 
Spectrochim. Acta, 32A, 1319-1322 (1976).   pdf

 

 
   
 
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